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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP10
All Species:
13.64
Human Site:
S253
Identified Species:
25
UniProt:
Q14694
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14694
NP_005144.2
798
87134
S253
P
G
A
D
F
G
Q
S
C
F
P
A
E
A
G
Chimpanzee
Pan troglodytes
XP_511147
902
98075
S379
P
G
A
D
F
G
Q
S
C
F
P
A
E
A
G
Rhesus Macaque
Macaca mulatta
XP_001111197
930
101558
S385
P
G
A
D
F
G
Q
S
C
F
P
A
E
A
G
Dog
Lupus familis
XP_536761
834
90976
S289
H
G
A
D
L
E
Q
S
C
L
S
T
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P52479
792
87004
P250
H
E
A
D
F
E
Q
P
C
L
P
A
D
S
L
Rat
Rattus norvegicus
Q3KR59
794
87293
Q250
C
R
E
T
D
F
E
Q
P
C
L
P
T
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510486
793
87073
R259
A
G
R
G
S
P
L
R
T
A
V
A
Q
P
F
Chicken
Gallus gallus
Q5ZJN4
785
86537
T252
G
R
D
S
P
L
R
T
A
V
V
Q
P
Y
A
Frog
Xenopus laevis
Q2NL57
791
87545
D251
E
Q
S
C
I
P
S
D
N
G
R
E
S
P
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122220
379
42828
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794239
817
88996
S255
S
D
D
Q
Q
I
K
S
D
S
H
D
E
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPS3
551
60422
N31
K
P
T
K
D
P
Q
N
S
K
D
K
C
V
G
Baker's Yeast
Sacchar. cerevisiae
Q01477
912
101898
K298
K
K
K
T
E
V
K
K
E
D
A
K
Q
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
84.4
85.4
N.A.
83.3
84.2
N.A.
79.6
78.5
70.5
N.A.
N.A.
N.A.
24.4
N.A.
36.6
Protein Similarity:
100
85.6
85.1
89
N.A.
88.8
88.7
N.A.
86.9
84.3
79.3
N.A.
N.A.
N.A.
35.5
N.A.
52.8
P-Site Identity:
100
100
100
60
N.A.
46.6
0
N.A.
13.3
0
0
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
60
N.A.
60
6.6
N.A.
20
13.3
6.6
N.A.
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.5
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
39
0
0
0
0
0
8
8
8
39
0
31
8
% A
% Cys:
8
0
0
8
0
0
0
0
39
8
0
0
8
0
0
% C
% Asp:
0
8
16
39
16
0
0
8
8
8
8
8
8
16
0
% D
% Glu:
8
8
8
0
8
16
8
0
8
0
0
8
39
0
0
% E
% Phe:
0
0
0
0
31
8
0
0
0
24
0
0
0
0
8
% F
% Gly:
8
39
0
8
0
24
0
0
0
8
0
0
0
0
39
% G
% His:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
8
8
8
0
0
16
8
0
8
0
16
0
0
0
% K
% Leu:
0
0
0
0
8
8
8
0
0
16
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% N
% Pro:
24
8
0
0
8
24
0
8
8
0
31
8
8
16
0
% P
% Gln:
0
8
0
8
8
0
47
8
0
0
0
8
16
0
0
% Q
% Arg:
0
16
8
0
0
0
8
8
0
0
8
0
0
0
8
% R
% Ser:
8
0
8
8
8
0
8
39
8
8
8
0
8
16
0
% S
% Thr:
0
0
8
16
0
0
0
8
8
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
16
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _